Macrophage’s little helper: vitamin A directs alternatively activated monocyte-derived macrophages to tissue-resident macrophages
نویسندگان
چکیده
منابع مشابه
Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct.
Macrophages adopt an alternatively activated phenotype (AAMs) when activated by the interleukin-4receptor(R)α. AAMs can be derived either from proliferation of tissue resident macrophages or recruited inflammatory monocytes, but it is not known whether these different sources generate AAMs that are phenotypically and functionally distinct. By transcriptional profiling analysis, we show here tha...
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ژورنال
عنوان ژورنال: Cellular & Molecular Immunology
سال: 2017
ISSN: 1672-7681,2042-0226
DOI: 10.1038/cmi.2017.58